Background: Only data of published study results are available to the scientific community for further use such as informing future research and synthesis of available evidence. If study results are reported selectively, reporting bias and distortion of summarised estimates of effect or harm of treatments can occur. The publication and citation of results of clinical research conducted in Germany was studied.Methods: The protocols of clinical research projects submitted to the research ethics committee of the University of Freiburg in 2000 were (...) analysed. Published full articles in several databases were searched and investigators contacted. Data on study and publication characteristics were extracted from protocols and corresponding publications.Results: 299 study protocols were included. The most frequent study design was randomised controlled trial , followed by uncontrolled studies , laboratory studies and non-randomised studies . 182 were multicentre studies including 97 international collaborations. 152 of 299 had commercial funding and 46 non-commercial funding. 109 of the 225 completed protocols corresponded to at least one full publication ; the publication rate was 48%. 168 of 210 identified publications were cited in articles indexed in the ISI Web of Science. The median was 11 citations per publication .Conclusions: Results of German clinical research projects conducted are largely underreported. Barriers to successful publication need to be identified and appropriate measures taken. Close monitoring of projects until publication and adequate support provided to investigators may help remedy the prevailing underreporting of research. (shrink)

This first volume of Wittgenstein's Last Writings on the Philosophy of Psychology was written between October 1948 and March 1949, when the philosopher had moved to Dublin and was having one of his most fruitful working periods. He then finished work which he had begun in 1946 and which in its entirety constitutes the source material for Part II of the "Philosophical Investigations". When, later in 1949, Wittgenstein composed the manuscript for Part II he selected more than half the remarks (...) for it from the Dublin manuscript. Although this material is a direct continuation of the writings which make up the two volumes of the Remarks on the Philosophy of Psychology it deserves more than they to be regarded as a "preliminary study" for the second part of Wittgenstein's "chef-d'oeuvre". (shrink)

It is shown that the covariance together with the quantum principle speak for an affinely connected structure which, for distances greater than Planck’s length, goes over in a metrically connected structure of space-time.

This bilingual edition of the Remarks on the Philosophy of Psychology presents the first English translation of an essential body of Wittgenstein's work. It elaborates Wittgenstein's views on psychological concepts such as expectation, sensation, knowing how to follow a rule, and knowledge of the sensations of other persons. It also shows strong emphasis on the "anthropological" aspect of Wittgenstein's thought.

_Zettel, _ an en face bilingual edition, collects fragments from Wittgenstein's work between 1929 and 1948 on issues of the mind, mathematics, and language.

Synchronistic or psi phenomena are interpreted as entanglement correlations in a generalized quantum theory. From the principle that entanglement correlations cannot be used for transmitting information, we can deduce the decline effect, frequently observed in psi experiments, and we propose strategies for suppressing it and improving the visibility of psi effects. Some illustrative examples are discussed.

Purpose: Commenting on the transcript of a lecture. Findings: The document reconstructs the development of the original 1973 lecture by Heinz von Foerster into his best-known paper, On Constructing a Reality. Many aspects of that paper can be identified as being shaped through interaction with the audience. Implications: The lecture documented here was a forerunner of a central paper in constructivism.

WALTER BURLEIGH, Von der Reinheit der Kunst der Logik. Erster Traktat: Von den Eigenschaften der Termini. Übersetzt und mit Einfuhrung und Anmerkungen herausgegeben von Peter Kunze. Lateinisch-deut...

The paper is based upon a conception of norms as prescriptions which are neither true nor false. Two norms may be said to contradict one another when the conjunction of (the descriptions of) their contents is a logical contradiction. A norm is said to entail another norm when the first norm and the negation-norm of the second contradict one another. By the negation-norm of an obligation is understood a permission "to the contrary", and by the negation-norm of a permission an (...) obligation "to the contrary". On the basis of these definitions it can be shown that the axioms and theorems of first order standard deontic logic are "normative tautologies". Norms of higher order may be viewed as prescriptions "transmitting the will" of a higher or sovereign authority through a lower or sub-ordinate authority to the norm-subjects. Under this conception of the orders, it is provable that a "complete" system of deontic logic is S4-like. (shrink)

Symposium in Helsinki, 24-27 August 1970 / Entretiens de Helsinki, 24-27 août 1970.

Intent and mitigating circumstances play a central role in moral and legal assessments in large-scale industrialized societies. Al- though these features of moral assessment are widely assumed to be universal, to date, they have only been studied in a narrow range of societies. We show that there is substantial cross-cultural variation among eight traditional small-scale societies (ranging from hunter-gatherer to pastoralist to horticulturalist) and two Western societies (one urban, one rural) in the extent to which intent and mitigating circumstances influence (...) moral judgments. Although participants in all societies took such factors into account to some degree, they did so to very different extents, varying in both the types of considerations taken into account and the types of violations to which such considerations were applied. The particular patterns of assessment characteristic of large-scale industrialized societies may thus reflect relatively recently culturally evolved norms rather than inherent features of human moral judgment. (shrink)

It is argued that, under the assumption that the strong principle of equivalence holds, the theoretical realization of the Mach principle (in the version of the Mach-Einstein doctrine) and of the principle of general relativity are alternative programs. That means only the former or the latter can be realized—at least as long as only field equations of second order are considered. To demonstrate this we discuss two sufficiently wide classes of theories (Einstein-Grossmann and Einstein-Mayer theories, respectively) both embracing Einstein's theory (...) of general relativity (GRT). GRT is shown to be just that “degenerate case” of the two classes which satisfies the principle of general relativity but not the Mach-Einstein doctrine; in all the other cases one finds an opposite situation.These considerations lead to an interesting “complementarity” between general relativity and Mach-Einstein doctine. In GRT, via Einstein's equations, the covariant and Lorentz-invariant Riemann-Einstein structure of the space-time defines the dynamics of matter: The symmetric matter tensor Ttk is given by variation of the Lorentz-invariant scalar densityL mat, and the dynamical equations satisfied by Tik result as a consequence of the Bianchi identities valid for the left-hand side of Einstein's equations. Otherwise, in all other cases, i.e., for the “Mach-Einstein theories” here under consideration, the matter determines the coordinate or reference systems via gravity. In Einstein-Grossmann theories using a holonomic representation of the space-time structure, the coordinates are determined up to affine (i.e. linear) transformations, and in Einstein-Mayer theories based on an anholonomic representation the reference systems (the tetrads) are specified up to global Lorentz transformations. The corresponding conditions on the coordinate and reference systems result from the postulate that the gravitational field is compatible with the strong equivalence of inertial and gravitational masses. (shrink)

-- v. 3. Truth, knowledge, and modality.

Humanism, modernity, and scientific rationality are examined critically in these collected essays.

In several works on modality, G. H. von Wright presents tree structures to explain possible worlds. Worlds that might have developed from an earlier world are possible relative to it. Actually possible worlds are possible relative to the world as it actually was at some point. Many logically consistent worlds are not actually possible. Transitions from node to node in a tree structure are probabilistic. Probabilities are often more useful than similarities between worlds in treating counterfactual conditionals.

'The most thorough and scrupulous of contemporary students of induction' (the execrable Quinton 1993, p. 172).